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Health & Wellbeing

Literary Review of Trauma Disorders with Focus on Psychophysiological Concepts for Expanding Clinical Approaches

  • Alumni research project
  • by Joseph Perri
  • № 42
Research by

Joseph Perri

Current diagnostic and treatment approaches to trauma disorders in psychiatric medicine largely focus on generalised psychosocial divergence. An opportunity to expand perspectives in detailing patient experience has presented itself. A literary review of translational and direct research relating to changes within neurological structures and physiological responses suggests potential for biomarkers to be used in tandem with current clinical approaches, elevating psychiatric medicine to evolve, thereby creating a platform that includes psychophysiological approaches.

The development of this theory hinges upon the accessibility of cardiorespiratory, musculoskeletal, gastrointestinal, pain, and immunological data to be extant in current study to provide foundational evidence supporting the use of biomarkers within the diagnostics and treatment of trauma disorders.

Although a biomarker matrix could not be identified in these initial stages, current research supports a need for exploration in physiological divergence of trauma disorders, and deviations in the neuroarchitecture of impacted individuals.

The present work predicts a strong corollary relationship between immunology and trauma, as increases in pro-inflammatory markers may provide insights into why only a minority of those exposed to potentially traumatic events develop Posttraumatic Disorders.

Additionally, divergent immunology provides emergent data in neurological deviations that suggest a biological basis in resultant Posttraumatic symptomology. Biomarkers are still far from producing precision psychiatric medicine; however, exploring immunology as it relates to the development, resurgence, and symptomology of trauma disorders will pave the way to becoming a valuable instrument in psychiatric toolkits, creating enhanced efficacy in patient care.

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